Giants' John Harbaugh gets candid on 'shock sandwich' in first season | Exclusive

That may seem a bit disrespectful to Jameis Winston, who came off the bench when Jaxson Dart went down in Week 2 with a season-ending knee injury and is poised to start his second game for the Giants (2-1) on Sunday against the Arizona Cardinals.

McCarthy, the former first-round pick obtained from the Minnesota Vikings on Monday , Sept. 28, just finished his second practice with his new team on Thursday.

"I'd say all things are possible," Harbaugh told USA TODAY Sports in an exclusive conversation Thursday evening. "Nothing is not. Jameis is our quarterback and we're trying to win this game."